The research in this laboratory is focused around questions concerning chromosomal and molecular evolution in vertebrates with particular emphasis on natural populations of mice in the genus Peromyscus. Although this usually involves assessments of intraspecific (populational) polymorphism, the data are generally applicable to systematic interpretations and considerable attention is paid to the processes of speciation and the evolutionary history and phylogenetic relationships among species. The systematic relationships of the species studied are typically used to establish the experimental design of the hypotheses tested. Our current research emphases concern mtDNA sequence-based analyses of the phylogeogeography of the P. maniculatus group species, the evolution of DNA microsatellites within and among the species of Peromyscus and the genetics and evolutionary relevance of chromosomal fragile sites.

1. Walker ML, Chirhart SE, Moore AF, Honeycutt RL & Greenbaum IF (2006) Genealogical concordance and the specific status of Peromyscus sejugis. J Hered 97: 340-5
   
2. Chirhart SE, Honeycutt RL & Greenbaum IF (2005) Microsatellite variation and evolution in the Peromyscus maniculatus species group. Mol Phylogenet Evol 34: 408-15
   
3. Denison SR, Simper RK & Greenbaum IF (2003) How common are common fragile sites in humans: interindividual variation in the distribution of aphidicolin-induced fragile sites. Cytogenet Genome Res 101: 8-16
   
4. Dahm PF, Olmsted AW & Greenbaum IF (2002) Probability models and the applicability of statistical procedures in the identification of chromosomal fragile sites. Biometrics 58: 1028-31; discussion 1032-3
   
5. Berend SA, Hale DW, Engstrom MD & Greenbaum IF (2001) Cytogenetics of collared lemmings (Dicrostonyx groenlandicus). II. Meiotic behavior of B chromosomes suggests a Y-chromosome origin of supernumerary chromosomes. Cytogenet Cell Genet 95: 85-91
   
6. Chirhart SE, Honeycutt RL & Greenbaum IF (2000) Microsatellite markers for the deer mouse Peromyscus maniculatus. Mol Ecol 9: 1669-71
   
7. Smith LR, Hale DW & Greenbaum IF (2000) Systematic implications of chromosomal data from two insular species of Peromyscus from the Gulf of California. J Hered 91: 162-5
   
8. Dawson WD, Young SR, Wang Z, Liu LW, Greenbaum IF, Davis LM & Hall BK (1999) Mus and Peromyscus chromosome homology established by FISH with three mouse paint probes. Mamm Genome 10: 730-3
   
9. Greenbaum IF, Fulton JK, White ED & Dahm PF (1997) Minimum sample sizes for identifying chromosomal fragile sites from individuals: Monte Carlo estimation. Hum Genet 101: 109-12
   
10. McAllister BF & Greenbaum IF (1997) How common are common fragile sites: variation of aphidicolin-induced chromosomal fragile sites in a population of the deer mouse (Peromyscus maniculatus). Hum Genet 100: 182-8
    
11. Berend SA, Hale DW, Engstrom MD & Greenbaum IF (1997) Cytogenetics of collared lemmings (Dicrostonyx groenlandicus). I. Meiotic behavior and evolution of the neo-XY sex-chromosome system. Cytogenet Cell Genet 79: 288-92
    
12. Dominguez AM, Smith SA & Greenbaum IF (1995) Susceptibility of heterochromatin to aphidicolin-induced chromosomal breakage. Hum Genet 96: 516-20
    
13. Böhm U, Dahm PF, McAllister BF & Greenbaum IF (1995) Identifying chromosomal fragile sites from individuals: a multinomial statistical model. Hum Genet 95: 249-56
    
14. Kingswood SC, Kumamoto AT, Sudman PD, Fletcher KC & Greenbaum IF (1994) Meiosis in chromosomally heteromorphic goitered gazelle, Gazella subgutturosa (Artiodactyla, Bovidae). Chromosome Res 2: 37-46
    
15. Dahm PF & Greenbaum IF (1994) Reconsideration of the binomial and F distribution relationship as a test for nonrandomness of chromosomal breakage. Cytogenet Cell Genet 66: 214-5
    
16. Greenbaum IF, Gunn SJ, Smith SA, McAllister BF, Hale DW, Baker RJ, Engstrom MD, Hamilton MJ, Modi WS & Robbins LW (1994) Cytogenetic nomenclature of deer mice, Peromyscus (Rodentia): revision and review of the standardized karyotype. Report of the Committee for the Standardization of Chromosomes of Peromyscus. Cytogenet Cell Genet 66: 181-95
    
17. Reed KM, Sites JW Jr & Greenbaum IF (1992) Chromosomal synapsis and the meiotic process in male mesquite lizards, Sceloporus grammicus complex. Genome 35: 398-408
    
18. Reed KM, Sites JW Jr & Greenbaum IF (1992) Synapsis, recombination, and meiotic segregation in the mesquite lizard, Sceloporus grammicus, complex. II. Fission heteromorphism of the FM2 cytotype and evolution of chromosome 2. Cytogenet Cell Genet 61: 46-54
    
19. Reed KM, Sites JW Jr & Greenbaum IF (1992) Synapsis, recombination, and meiotic segregation in the mesquite lizard, Sceloporus grammicus, complex. I. Pericentric inversion heteromorphism of the F5 cytotype. Cytogenet Cell Genet 61: 40-5
    
20. Hogan KM, Jarrell GH, Ryder EJ & Greenbaum IF (1992) Heterosynapsis and axial equalization of the sex chromosomes of the northern bobwhite quail. Cytogenet Cell Genet 60: 131-4
    

Publications list from Pubmed